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Oncotest Tumor Collection

patientderivedpatient-derived vs. cell line-derived model

You're looking for

patient-derived xenograft models with
  • good clinical predictivity
  • known sensitivity profiles for standard of care compounds
  • complete sets of characterization data

 

Oncotest offers 

more than 325 established xenograft models

  • most solid tumor types represented
  • passaged as tumor fragments, not cell suspensions
  • early-passage master stocks guarantee long-term availability of material

histological differences between patient and cell line derived colon cancer xenografts


comprehensive profiling

  • patient characteristics
  • chemosensitivity profiles for SOC compounds
  • more than 1200 data sets to help you choose the most appropriate model for your study
mutational, gene and protein expression, immunohistochemistry analyses allow customization of tumor panels for a target- or pathway-based approach





sample repository
  • Oncotest tumor and cell line material is available as frozen or formalin fixed tissue or slides, protein lysates, serum from tumor bearing mice, or purified nucleic acids

predictivity

  • Oncotest‘s patient-derived tumor xenograft models retain relevant characteristics of donor material such as tumor architecture, molecular and protein alterations, making these models highly predictive with respect to the clinical situation